会议介绍：
近年来，新的技术、分析方法以及基于人口的大型生物样本库的建立推动着基因发现方面的进展，而这些最新进展使得我们对人类基因组在广度和深度上都获得了前所未有的理解。
此次会议旨在讨论科学家和临床医生如何更好地利用这些知识来更准确地识别有疾病风险的个体，辨识有前景的治疗策略，以及将这些疗法与最有可能从中受益的个体和人群相匹配。
今年我们将关注两大复杂疾病的发病率 ： 心血管疾病和癌症。我们希望结合统计遗传学和转化研究，进而探讨个体水平和群体水平上的遗传变异如何影响健康和疾病。
会议将以研讨会为切入点，心血管疾病为重点，围绕遗传流行病学和精准医学之间的转化、如何在临床决策中更好地利用突变检测和多基因风险评分展开讨论。接下来，我们将进一步研究生殖的基因组学，具体是指运用单细胞方法探究早期胚胎发育和再生医学中的细胞重编程。会议最后一个环节将集中讨论基因组学和表观基因组学如何给利用癌症机制漏洞的靶向治疗带来启示。
欢迎您注册参会，与《自然-遗传学》《自然-通讯》编辑，以及来自英国埃克塞特大学、美国国家癌症研究所、美国圣裘德儿童研究医院、香港大学、中国医学科学院、同济大学等国内外知名院校的权威学者进行面对面的交流。
Conference Introduction:
Recent progress in genetic discovery, fuelled by novel technologies and analytical approaches as well as the establishment of population-based mega-biobanks, has led to unprecedented under-standing of the human genome, both in breadth and depth.
The aim of this conference is to discuss how scientists and clinicians can best leverage this knowledge to identify individuals at risk of diseases with more precision, to discern promising therapeutic strategies and to match these therapies to people and populations most likely to benefit from them.
This year we focus on the two largest categories of complex disease morbidity - cardiovascular disease and cancer - and we hope to bring together statistical genetics and translational research to explore how individual and population level genetic variation influence health and disease.
We will begin with a workshop on the translation of genetic epidemiology into precision medi-cine and how best to use mutation detection and polygenic risk scores in clinical decision mak-ing, with an emphasis on cardiovascular diseases. We will further examine the genomics of re-production, and specifically single cell approaches to investigate early embryonic development and the reprogramming of cells for regenerative medicine. The last session will focus on how ge-nomics and epigenomics can inform targeted therapies designed to exploit mechanistic vulnera-bilities in cancer.
Welcome to register and have a face to face communication with experts from Nature Genetics, Nature Communication, University of Exeter Medical School-UK, National Cancer Institute Divi-sion of Cancer Epidemiology & Genetics-USA, St. Jude children’s research hospital-USA and so on.
